evaluation of serum albumin level and its effect on prognosis in patients admitted to intensive care unit

evaluation of serum albumin level and its effect on prognosis in patients admitted to intensive care unit    valizadeh hasanloei ma [1] , norozinia h [2] *, shateri k [3] , bakhtyari l [4] , hosseinpour h [5]     received: 18 sep , 2013 accepted: 21 nov , 2013   abstract   background & aims : albumin and globulin are the largest components of the body proteins. albumin is a protein made in the liver and 50-60% of the total protein.   materials &methods;: in this prospective study, 225 patients who admitted to intensive care unit were enrolled. serum albumin level on admission to the icu were recorded and patients were followed. data analyzed with spss.   result: mean albumin levels were 3.52±0.87, in 49 trauma patients 3.74±1, in 36 patients with cancerous 3.41± 0.77, in 38 patients with lung disease 3.63±0.7, in 30 patients with cns disorders 3.61 ±0.77 and in 72 patients with other underlying diseases 3.26±0.92 gr / dl, respectively. according to chi-square test there were no significant correlation between albumin level and the need for mechanical ventilation in all patients (p = 0.47), trauma (p =0.44), patients with cancerous (p=0.70), lung disease (p =0.42) patients) cns0(p=0.24) and patients with other underlying conditions (p =0.24). also according to chi-square test there were no significant correlation between albumin level and mortality in all patients (p =0.36), trauma (p =0.96), cancerous patients (p =0.16), lung disease (p= 0.78), patients with cns disorders (p =0.52) and patients with other underlying diseases (p =0.13). our results showed there is no correlation between albumin levels in patients (trauma, pulmonary, cns, cancer, and other underlying diseases) and the total patients admitted to the intensive care unit. conclusion: although in several studies albumin has known as an indicator of the metabolic status of patients requiring mechanical ventilation, mortality and length of stay, in our study, there is no significant correlation between albumin level and those items. needed for further studies.keywords: protein, albumin, apache scoring systems, , intensive care unit     address: ershad ave, imam khomeini hospital, department of anesthesiology & intensive care medicine , tel: (+98)0441-33469931   email : [email protected]   [1] anesthesiologis t, fellowship of intensive care medicine, assistant professor of urmia medical sciences university.   [2] anesthesiologist, associate professor of urmia medical sciences university (corresponding author).  [3] internist, gastrointestinal sub specialist, assistant professor of urmia medical sciences university.  [4] general practitioner, qom medical sciences university.  [5] general practitioner, urmia medical sciences university.